The prescription validation previously in place no longer applies and the limit of two pens per prescription has now been lifted.

Prescribers are reminded that Medicines and Health Regulatory Agency (MHRA) guidelines recommend patients carry two adrenaline auto-injectors at all times.

Pharmacies are able to place orders and hold stock of EpiPen Jr 0.15mg and EpiPen 0.3mg AAI devices so that patient prescriptions can be fulfilled the same day.

Please place your order through Alliance Healthcare, stating your account number in the request.

Hospitals are able to place orders and hold stock of EpiPen Jr 0.15mg and EpiPen 0.3mg AAIs.

Please place your order through Alliance Healthcare, stating your account number in the request.

To support children and young adults who may be at risk of anaphylaxis whilst away from home, the Human Medicines (Amendment) Regulations 2017 allows schools, without the need for a prescription, to purchase and hold supply of adrenaline auto-injectors. Regulations allow the purchase of a reasonable number of adrenaline auto-injectors for use on an occasional basis and as required.

Orders for EpiPen Jr 0.15mg and EpiPen 0.3mg can be made through your local pharmacy. Please provide your pharmacy with a letter written on your school’s headed paper and signed by the principal or headteacher. The pharmacy will then send the request to Mylan’s distribution partner, Alliance Healthcare.

Extended Use Beyond Labelled Expiry Date for Specific Lots of EpiPen® 0.3mg Adrenaline Auto-Injectors

In August 2019, Mylan was granted approval to a variation to permanently extend the shelf life of EpiPen 0.3mg auto-injectors from 20 months to 24 months.

For AAIs already on the market, prior to the permanent extension of shelf life above, Mylan UK obtained approval from the MHRA to extend the use of specific lot (batch) numbers of EpiPen® 0.3mg auto‐injectors, 4 months beyond the labelled expiry date. The affected lot numbers are listed in the table below.

This batch-specific extended use does not apply to EpiPen® 0.15mg AAI or any lot number of EpiPen 0.3 mg auto-injectors not specified. It is important that patients must continue to adhere to the labelled expiry date on any EpiPen® not covered by the lot numbers below.

EpiPen® 0.3mg (single pack)

EpiPen® 0.3mg (twin pack)

Further information

You can find the lot number on the end-flap of the box and on the EpiPen® itself. If you’re unsure whether your EpiPen® is affected, talk to your pharmacist.

At the end of the extended use period (the end of the month listed under “Extended Expiry Date” in the table above), you will still need to obtain a new auto-injector by the usual means.

Please note that the information provided in this communication supersedes any other communication that patients receive from the Expiry Alert Service.

Telephone: +44 (0)1707 853 000

Medical Information e-mail: info@remove-this.mylan.co.uk