Side-effects

Transient side-effects such as pallor, tremor, anxiety, palpitations, headache and dizziness can occur within 5 to 10 minutes of injection, but these are usually mild and confirm that a therapeutic dose has been given.

Although serious events such as pulmonary oedema or hypertension have been reported with adrenaline, these are usually associated with overdose and with the IV, rather than the IM or SC route.14

Some HCPs perceive adrenaline as dangerous because of its cardiovascular side effects; however, the risks of anaphylaxis outweigh the risks of adrenaline for the vast majority of patients.

If there is any doubt, it is generally better to administer adrenaline.

  • 14 - Simons FER. J Allergy Clin Immunol 2010;125:S161-81.

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UK/EPI/11/0059 October 2011