Can EpiPen® be given to patients with a sulpha allergy?

Yes. Although EpiPen® contains sodium metabisulphite, a patient with a sulpha allergy is allergic to drugs that contain the sulphonamide group, but not to drugs containing sulphur, sulphites, or sulphates. The allergy is specific to the sulphonamide group and does not predispose a patient to allergy with any other compounds containing sulphur.