Which patients should use adrenaline with caution?

Adrenaline should be used with caution in patients who have cardiac arrhythmias, coronary artery or organic heart disease, hypertension, or in patients who are on drugs that may sensitise the heart to arrhythmias, e.g., digitalis, diuretics, quinidine, or other anti-arrhythmics. In such patients, adrenaline may precipitate or aggravate angina pectoris as well as produce ventricular arrhythmias.
It should be recognised that the presence of these conditions is not a contraindication to adrenaline administration in an acute, life-threatening situation.