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When to use your EpiPen®

Anaphylaxis is a medical emergency which must be treated quickly.

If someone has symptoms of anaphylaxis you should:

  • Use an Adrenaline Auto-Injector (AAI) if available
  • Call 999 immediately
  • Remove trigger if possible
  • Make sure the person lies down
  • Administer a second AAI if there is no improvement in symptoms in 5 minutes

Recognise the symptoms

Symptoms of an allergic reaction usually develop within a few minutes of being exposed to the allergen. Symptoms will vary from person to person so it is important to discuss your symptoms with your doctor and be clear on what to look out for. Anaphylaxis usually develops suddenly and gets worse very quickly.

Severe allergic reaction (anaphylaxis) symptoms include:

  • Feeling lightheaded or faint
  • Breathing difficulties, such as fast, shallow breathing
  • Swelling of the throat and mouth
  • Blue skin or lips
  • Confusion and anxiety
  • Collapsing or losing consciousness

Mild to moderate allergic reaction symptoms include:

  • Red, raised, itchy rash
  • Abdominal pain, nausea and/or vomiting
  • Itchy, red, watering eyes
  • Sneezing, itchy, runny or blocked nose
  • Swollen lips, tongue, eyes or face

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If you get any side effects or have a device failure, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. Please report side effects or device failures with any medicine or vaccine to the medicines regulator MHRA through the Yellow Card Scheme.
It is easiest and quickest to report side effects and device failures online via the Yellow Card website:  https://yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in the Google Play or Apple App Store.
Alternatively, prepaid Yellow Cards for reporting are available by writing to FREEPOST YELLOW CARD (no other address details necessary), by emailing yellowcard@mhra.gov.uk, by telephoning the Commission on Human Medicines (CHM) free phone line: 0800-731-6789, or by downloading and printing a form from the Yellow Card section of the MHRA website. You can also report side effects and device failures direct to the marketing authorisation holder at pv.uk@viatris.com.   


This website is owned and managed by Viatris.

This website is intended for UK patients who have been prescribed EpiPen®. We recommend that you read the 0.3 mg patient information leaflet or 0.15 mg patient information leaflet carefully before using EpiPen®. If you’re a Healthcare Professional, please click here.

EPI-2021-0592 August 2023

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